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DOI: 10.1161/HYPERTENSIONAHA.109.132522 Arsenian, M
Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) classified as a selective ghrelin/growth hormone secretagogue receptor (GHS-R) agonist
Zingg, J.M., Meydani, M., 2019
Additional preclinical research has examined the compound in energy homeostasis, appetite suppression, and peripheral metabolic signalling models
1 Introduction 1.1 Atherosclerosis and coronary artery disease Coronary artery disease (CAD) is a cardiovascular condition occuring due to atherosclerotic plaque accumulation in the epicardial arteries, whether obstructive or non-obstructive ( Inflammation plays a key role in the formation of atherosclerotic plaquesthe primary pathological mechanism underlying CAD ( (IFN- ) and tumour necrosis factor (TNF)- , produced by immune cells, endothelial cells, platelets and fibroblasts are associated with atherosclerosis onset and progression
