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NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme that fuels cellular energy production, protects DNA, and plays a key role in brain health and aging
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In rodent studies, exendin-4 and dulaglutide have been detected in the brain following systemic administration, supporting their ability to engage central GLP-1 receptors, and these compounds are generally considered to be capable of penetrating the BBB (rskov et al., 1996
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Additionally, the combo therapy led to greater reductions in abdominal fat and inflammation-related biomarkers, highlighting its potential as a more sustainable and health-optimized obesity treatment strategy
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