Our view: Oral GLP-1 supplementation, combined with good nutrition and consistent habits, is the more evidence-supported non-prescription option
Kuo B, McCallum RW, Koch K et al
Specifically, these mechanisms of action cover multiple aspects, such as activation of the cAMP-PKA signaling pathway, inhibition of pro-inflammatory cytokine release, and also activation of the AMPK signaling pathway, promoting the expression of anti-inflammatory genes, and regulation of macrophage function [26]
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And I think that needs to be continued as we progress into using these medications for longer periods of time, to ensure that we know the entirety of the risks and the benefits of them