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Researchers followed more than 2,200 adults who had lost an average of 15% of their body weight over 76 weeks using semaglutide

Am J Physiol 279:R1449R1454 Bertsch T, McKeirnan K (2018) ITCA 650

If the underlying issue isnt addressed - whether its inflammation, structural imbalance, or nervous system dysregulation - results may be temporary or minimal