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Description

The net effect is improved tumor cell kill, reduced systemic exposure and lower cardiotoxicity compared with free doxorubicin, positioning chitosan-based platforms as a promising next-generation approach for breast cancer therapy [67, 91]

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Finally, a cell cycle-dependent variation of the amount of GSTP1-1-TRAF2 complex existing in cells was detected, with a maximum in G 0 /G 1 and a strong decrease in S, G 2 , and M phases

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