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Drawbacks include doubled medication costs (approximately $400-600 monthly vs $200-300 for Sermorelin alone), increased side effects particularly appetite stimulation from ghrelin receptor activation, twice-daily injections reducing convenience, and complexity of managing two peptide protocols
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In addition, patients with severe liver, kidney problem, uncontrolled diabetes and thyroid problem would be contraindicated as well
Atlanta Peptide Therapy: 2026 ATL Guide A plain guide to peptide therapy across metro Atlanta: what it costs at clinics, med spas, and telehealth, who tends to use it here, and how pharmaceutical-grade peptides reach any Atlanta-area address without a drive across the Perimeter
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