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The nitrogen atoms on the histidine imidazole ring and glycine amine backbone coordinate with Cu with extremely high binding affinity, forming a stable bioavailable chelate complex
Chromatofocusing of glutathione S-transferases from research subjects kidney [PMID: 6719022] Laboratory literature summary: Chromatofocusing of glutathione S-transferases from research subjects kidney
Wound Healing A GHK-Cu collagen dressing produced a 9-fold increase in collagen content in healthy rats
Topical GHK-Cu can also slightly irritate the skin barrier, especially if the skin is sensitive, dry, or already inflamed