PIONEER 3 study design 1,4 In a double-blind, double-dummy trial with a primary endpoint of mean change in A1C from baseline to 26 weeks, 1864 adult patients with type 2 diabetes on metformin alone or metformin with a sulfonylurea were randomized to RYBELSUS 3 mg (n=466), RYBELSUS 7 mg (n=465), RYBELSUS 14 mg (n=465), or Januvia 100 mg (n=467), all once daily
Tirzepatide may have several benefits for kidney function, particularly by improving blood sugar control and supporting weight loss, both of which can reduce the strain on the kidneys
The supported project will be conducted in a real-world residential treatment center where patients with opioid use disorder will complete momentary assessments of mood, craving, and decision-making throughout a residential treatment period
What Baclofen Does Baclofen works by activating GABA-B receptors in the brain and spinal cord, which helps reduce muscle spasms and stiffness
Psychologist Jane Hobart, PsyD at Aspire Psychology shares more about what to expect, as well as what to look out for while on a GLP-1