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Reported effects may include: Mild bloating or stomach discomfort Nausea Headache Skin rash Unpleasant taste (with sublingual use) Stop the medication and contact your provider promptly if you develop: Persistent abdominal pain or vomiting Wheezing or shortness of breath Severe rash or swelling Any unusual or worsening symptoms Trouble breathing Swelling of face, lips, or tongue Severe allergic reaction Chest pain, severe dizziness, or fainting Take exactly as prescribed
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The doses of GLP-1 provided by semaglutide and tirzepatide are far greater than the body would naturally expect to receive, he says, which may suppress the body's ability to secrete GLP-1 on its own
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