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Nasal coadministration of insulin with D- or L-penetratin elevated the hippocampal insulin level both 15 and 60 min after administration, for subsequent delivery into deeper brain regions (Kamei and Takeda-Morishita, 2015)

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Diclofenac (50 g/mL) served as a positive control

Ozempic is also approved for reducing the risk of major cardiovascular events in adults with type 2 diabetes and heart disease