Table 1 List of Clinical Trials Evaluating the Cardiovascular Efficacy and Safety of GLP-1 RAs GLP-1 RA, glucagon-like peptide-1 receptor agonist
Common mechanisms of ferroptosis including iron overload, lipid peroxidation, GPX4 inhibition, and system Xc inhibition in obesity, which lead to decrease of GSH, increased ROS, and even ferroptosis
As a risk to a breastfed child cannot be excluded, Semaglutide should not be used during breast-feeding
However, some individuals may find one medication more suitable than the other, depending on different factors
Cost-Effectiveness of Semaglutide in research subjects With metabolic research models [PMID: 39772331] Laboratory literature summary: Cost-Effectiveness of Semaglutide in research subjects With metabolic research models and Cardiovascular Disease