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Inhibiting mTOR signaling in CAR T cells alters immunometabolism and enhances function Intrigued by our pre- and post-infusion results suggesting a significant role for mTOR activity on the efficacy of CAR T cells of LTR, we asked whether we could harness the mTOR pathway to enhance antitumor activity of CAR T cells of STR

In neuropharmacology, such interactions are particularly important given the central nervous system's sensitivity and the frequent use of polypharmacy

Understanding the biology and the human clinical trial data helps you decide whether a trial makes sense for you

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