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Metformin mitigates autoimmune insulitis by inhibiting Th1 and Th17 responses while promoting Treg production
Besides neonates, they both can be used for the rest of the population including pediatrics, adults and the geriatric community
Animal studies show substantial evidence across stroke models (full functional recovery in spatial memory, motor coordination, balance), Parkinsons models (protection of dopaminergic neurons, near-complete prevention of mortality), multiple sclerosis models (significantly less brain damage), and traumatic brain injury (reduced hemorrhage and edema)
Truong, V
Mechanisms of ferroptosis
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