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Rather than directly activating GABA-A receptors, the peptide appears to maintain homeostasis of the entire GABA receptor complex, preventing the desensitization and compensatory changes that produce tolerance and dependence
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Proc Natl Acad Sci USA 2020;117:3118997
Neurophysiological mechanisms underlying cortical hyper-excitability in amyotrophic lateral sclerosis: a review
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