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In lab experiments, Retatrutide blocked the metabolic changes caused by the fat cells and caused the YAP protein to be destroyed
doi:10.1056/NEJMoa2301972 PubMed: This landmark study demonstrated 24.2% mean weight loss at 48 weeks with the 12mg dose in 338 adults with obesity, establishing retatrutide as the most effective obesity medication tested to date
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J Am Acad Dermatol , 39(4 Pt 1):578589
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