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As the process of spermatogenesis declines, the volume of the testis, height of the germinal epithelium, number of sexual lineage cells, and percentage of normal and viable sperms witness a reduction, as well
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For people with type 2 diabetes, the average weight loss can be lower than in non-diabetic obesity trials (because diabetes, insulin use, and metabolic factors can influence outcomes)
The SELECT trial demonstrated cardiovascular benefits of semaglutide independent of weight loss, leading to a cardiovascular risk reduction indication that does not require a specific BMI
J Investig Med 66:710
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