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Due to historically higher rates of side effects (especially blood pressure elevation) with intranasal delivery, the injection is generally preferred for both efficacy and safety

Acknowledgements The authors would like to thank Servier, Marcel Tisch, B-Gideon-Bergheim, Long Li, Fang-fang-yang, Helicase 11 & Rahel-Khdhr for allowing us to use and modify their illustrations available at Bioicons.com and SciDraw.io in our figures

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Semaglutide and tirzepatide represent the two most-studied GLP-1 therapies available through PlexusDx

According to other recent analyses, tirzepatide, retatrutide, and survodutide all significantly reduce liver fat without showing signs of worsening liver fibrosis markers [131]