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Cell 184 , 35023518.e33 (2021)
Acetoacetyl-CoA and an additional acetyl-CoA are converted to -hydroxy--methylglutaryl-CoA (HMG-CoA: 3-hydroxy-3-methylglutaryl-CoA) by mitochondrial HMG-CoA synthase (encoded by the HMGCS2 gene), an enzyme found in large amounts only in the liver and intestinal epithelial cells
Rotate sites to prevent irritation
Injection Therapy Outcomes Research indicates B12 injections rapidly restore serum levels and reverse neurological symptoms in most patients
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