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This might occur in complex cases where other treatment options are limited due to contraindications, intolerances, or patient-specific factors
All conditions were run in triplicate wells
This observation means that xCT blockage induces the accumulation of glutamate that is converted into -ketoglutarate instead of being used in glutamate-cysteine exchange and consequently that is why cysteine does not enter the cell and give rise to glutathione
Regul Pept 2003
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