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Casciani CU, Caruso U, Cravotto E, and et al

Medicare will offer limited weight loss drug coverage through the Medicare GLP-1 Bridge starting July 1, 2026, for eligible Part D beneficiaries who meet CMS rules

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Resulting variants, X(PC4)aX(PC4)d, were less active on procaspase-1 than X(PC2) and X(PC3) proteases, but were highly selective for procaspase-1 cleavage (Fig