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3,4 For instance, following diet-induced weight loss, there is an observed increase in ghrelin and GIP and decrease in leptin, peptide YY (PYY), cholecystokinin (CCK), amylin, insulin, and GLP-1 from baseline
This may make them useful for gut-focused goals, but it can also limit how much reaches the rest of the body
123 In an uncontrolled pilot study in 40 women with PCOS, the combination of myo-inositol and lipoic acid decreased male hormone levels, improved menstrual regularity, and reduced unwanted hair growth and BMI without affecting glucose or insulin parameters
