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Nonetheless, it is also clear that intra-islet GLP-1R signaling is essential for GSIS, with more evidence that an intra-islet paracrine GLP-1 signaling is physiologically present (212, 213) and necessary for -cell health under metabolic (214)
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Glucagon-like Peptide-1 and the Central/Peripheral nervous system: crosstalk in diabetes
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