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Semaglutide and tirzepatide are particularly effective when theyre combined with a healthy diet and regular physical activity

Note: Semaglutide carries an FDA boxed warning about the risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

[27], headache days per month significantly improved with semaglutide or liraglutide: the median change at 6 months was 4 days in the GLP-1 group versus 0 days in the control group ( p = 0.02)

It is important to distinguish between clinical evidence and anecdotal claims

Solari, P