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As everyone is different, it is impossible to say with 100% certainty how long a vitamin B12 injection lasts in the body

Serotonin syndrome symptoms include hyperthermia (core temperature above 38.5C), muscle rigidity, confusion, and autonomic instability

Thats why the FDAs own technical staff has recommended against expanded access, and the public health group Partnership for Safe Medicines calls them "popular, unproven, dangerous. As Peter Kolchinsky, managing partner of biotech investor RA Capital Management, puts it: Is the FDA going to stand on science or is it going to permit all kinds of snake oil to be readily available? The FDA meeting will last two days

That is the honest state of the field right now