The first and most popular is via an intramuscular injection
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The L-arginine component in particular has been studied pre-meal, with results showing increased postprandial GLP-1 when taken before eating
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Your body has its own natural limits about how much it produces and absorbs, so you cant really overdo it, which is why its so well tolerated and there are so few side effects. That said, injection site reactions, mild headaches and dizziness can occur, but she says theyre usually mild, short lived, and affect very few people