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Lower-strength research formats (2 mg or 3 mg lyophilised vials) require manual reconstitution with bacteriostatic water
Bismuth subsalicylate (Pepto-Bismol) is the most effective over-the-counter remedy
It makes constipation harder to resolve, increases the concentration of bile acids that irritate the gut lining, reduces the volume of protective mucus, and impairs the motility that probiotics are trying to support
The clinical trial data showed that using a lower starting dose (2 mg vs 4 mg initial) significantly reduced the incidence and severity of these symptoms
Any of the following: myocardial infarction, stroke, hospitalization for unstable angina or transient ischemic attack within the past 60 days before screening
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