novo nordisk new glp 1 Catalent paves the way for Novo's US GLP-1 expansion Novo, Lilly weight-loss drugs should

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Weight loss Available in NZ = Liraglutide high dose (Saxenda, daily injection) Self-funding needed ($500-600/month) Not available in NZ = Semaglutide (Ozempic, Wegovy) or Tirzepatide (Mounjaro), as of May 2023 Side effects, particularly upper gastrointestinal, are common with GLP-1 agonist initiation

For the evaluation of the effects of treatments on insulin sensitivity, insulin tolerance tests (ITT) were conducted 5 days after implementation of the GTTs, which allowed the proper recovery and washout of the animals

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material becomes more available to intestinal and pancreatic receptors while at lower doses, the intestinal route provides more direct exposure to the relevant receptor locations