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Hence, preserving the structural integrity of the cell membrane is a crucial concern that must be addressed during the fusion and extraction procedures (137)

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This family has attracted attention through their tissue-specific distribution of the incretin/glucagon related receptors which show unique effects and play a role in the variation in their respective functions

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Therefore, helices D1 and D2 of ShHTL4, ShHTL5, and ShHTL7 slid away from D3, resulting in larger pockets with a reduced chance of causing steric hindrance with ligands