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VD mitigates mitochondrial ROS via astrocytic glutathione (GSH) up-regulation and -glutamyl transpeptidase (GGT) activation [7], while VE preferentially quenches lipid peroxidation chains, potentiating endogenous antioxidants (SOD and catalase) in preclinical models [53]
In August 2025, the FDA approved Wegovy for MASH based on ESSENCE's findings
This treatment can be taken throughout the day, usually in three doses
This shift presents great opportunities and challenges to the food industry
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