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A preclinical study done in a mouse model of ALS (wobbler mice) showed that treatment with an ultra-high dose of methylcobalamin inhibits disease progression

You can - though you shouldnt need to if things go well with the first procedure

While the concentration of research within a single group has drawn some scientific criticism regarding independent verification, it has also produced an unusually coherent and detailed body of knowledge about a single compound

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Prolonged deficiency can also cause irreversible damage to the nervous system, leading to neurological disorders