For patients without absorption disorders, high-dose oral supplements of 1,000 to 2,000 mcg daily have been shown to be comparably effective at correcting mild to moderate deficiency at lower cost and greater convenience.
Emerging research highlighted that GM alterations such as declined beneficial bacteria communities or increased harmful gut mucin-degrading species can initiate pathogenesis of several diseases, including PD (168)
One is usually seen as more targeted, the other as more systemic, so using both is meant to cover more recovery pathways
It has not been stringently monitored for contaminants that can harm the user, so it is potentially unsafe and not to be used as a therapeutic drug
Also learn what clinical studies with alpha-lipoic acid have shown for diabetes, neuropathy, weight loss, Alzheimer's disease, and other conditions