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Of the 731 participants with HFpEF and BMI 30 kg/m 2 , 728 (99.6%) had elevated WHR (0.5)
Oral formulations cost slightly more ($289/month for oral semaglutide, $349/month for oral tirzepatide) but offer convenience for patients who prefer not to self-inject
Stable blood sugar Gallbladder removal has been linked to a potential increase in insulin resistance
The extended half-life results from reduced renal clearance, as the unbound peptide avoids the protective complexes that normally prevent glomerular filtration
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