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Clinical trials of sodiumglucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide 1 (GLP1) receptor agonists have shown beneficial effects of these agents on kidney outcomes in patients with type 2 diabetes mellitus
In der Forschung wird dies mit einer Hochregulation von Wachstumsfaktoren wie VEGF und der Interaktion mit dem NO-System in Verbindung gebracht
This effect is especially pronounced in patients already taking metformin, sulfonylureas, or insulin, where tirzepatide amplifies glucose-lowering effects
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