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Comparing tirzepatide and semaglutide Mechanism of action Semaglutide is a long-acting GLP-1 receptor agonist that stimulates glucose-dependent insulin secretion, suppresses glucagon release, delays gastric emptying and induces satiety
These often improve over time but can significantly affect quality of life
Usage Instructions Inject once weekly under the skin (abdomen, thigh, upper arm) Start at 0.25 mg weekly for 4 weeks, then increase as directed Doses may be raised to 0.5 mg, 1 mg, or 2 mg weekly Use at the same time each week (with or without food) Rotate injection sites to prevent skin irritation Side Effects Nausea, vomiting, diarrhea or constipation Loss of appetite Fatigue or headache Rare: pancreatitis, gallbladder problems, kidney injury, allergic reactions Increased risk of thyroid tumors in animal studies (not seen in humans) Side effects are often mild and improve with time
Food Supplement: 100 Capsules Serving Size: 1 Vegetarian Capsule RI = EU Reference Intake, * no RI available
The three primary areas recommended for GLP-1 injections are: The Abdomen: This is often the most popular site because it is easy to reach and typically has a consistent layer of subcutaneous fat
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