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Jul 30 2021;13(8)doi:10.3390/nu13082660

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A novobiocin derivative, XN4, triggers ferroptosis in gastric cancer cells via the activation of NOX4

[5] Notably, normal feedback mechanisms remain intact: elevated IGF-1 and GH can signal the hypothalamus and pituitary to modulate further hormone release, which may reduce the risk of extreme hormone levels

The Nuclear Factor Kappa B (NF-kB) signaling in cancer development and immune diseases