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In phase 2 trials, the drug showed up to 19% weight loss in patients after 46 weeks
doi: 10.1038/s41392-024-01931-z 16 HickeyJWBeckerWRNevinsSAHorningAPerezAEZhuCet al
Additionally, SeNP-MT 1-3 induced antioxidation pathways as recoded with increased glutathione peroxidase (GPX) and catalase (CAT) activities whereas maximum ratio (20.40%) of ascorbate to dehydro-ascorbate under SeNP-MT 2 was observed
Esto no mejorara la biodisponibilidad
However, no specific lifestyle intervention was introduced in addition to the study intervention of semaglutide or metformin
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