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For instance, a Taq1A polymorphism related to striatal dopamine D2 receptor density has been shown to affect the weight loss response to naltrexone/bupropion ( ARRB1 (rs140226575GA (Thr370Met)) ( A pilot study investigating GLP-1 receptor genes in patients with obesity has provided further insight ( Beyond type 2 diabetes and genetic variants, some physiological markers have been identified as predictors of weight loss response to anti-obesity medication
See Supplementary table 4A for details
Cases of Decreased Libido: A peer-reviewed case report documented a 36-year-old woman with obesity who developed sexual dysfunctionincluding decreased drive, genital dryness, and difficulty achieving orgasmwhile on tirzepatide
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Fatigue, constipation and headaches are also possible
