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What the evidence says (and what to expect) Clinical trials: Across four pivotal phase 3 trials, Contrave produced significant weight loss vs placebo over 56 weeks

These findings indicate that GLP-1RAs limit and stabilize the development of atherosclerotic plaques through anti-inflammatory mechanisms and by preventing vascular remodeling [62]

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Among all medicines worldwide, treatments for obesity and diabetes featuring GLP-1 agonists have surged to the top of the best-seller lists in the first half of 2025

It is known for its restorative properties, aiding in the regeneration and healing of various types of tissues, including muscles and nerves