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White WB, Cannon CP, Heller SR, Nissen SE, Bergenstal RM, Bakris GL, et al

Acute and chronic convection-enhanced muscimol delivery into the rat subthalamic nucleus induces antiseizure effects associated with high responder rates

Stabler 24 Patients with severe abnormalities should receive injections of 1000 g at least several times per week for 1 to 2 weeks, then weekly until clear improvement is shown, followed by monthly injections

Others experience it as a loss of pleasure or mild emotional flatness around food. Trial mood scores moved slightly better rather than worse, so the negative experience appears to be a minority signal that standard adverse-event tables do not capture well

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