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308 Rather than harboring stable resistance mutations, DTP cells adopt a slow-cycling or quasiquiescent phenotype driven by extensive epigenetic remodeling, transcriptional plasticity and metabolic reprogramming, which collectively constitute core maintenance programs that stabilize the DTP state under therapeutic pressure
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Surprisingly, Gclc KO mice showed no signs of liver damage, both by histology and serum biochemistry markers (Fig
Then add escalation, missed-dose, measurement, monitoring, and red-flag context
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