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This graduated escalation reduces the likelihood of side effects and gives the clinician time to assess patient response at each tier
Subgroup analyses by sex have not been prominently reported in published data, meaning sex-specific safety conclusions remain limited
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monthly injectable), or comorbidity label (MASH, HFpEF, sleep apnea) rather than head-to-head weight loss efficacy
The refrigerated environment slows molecular degradation processes while remaining easily accessible for routine manufacturing operations
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