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This GLP-1R plus strategy, combining GLP-1 RAs with other hormone-based medications that target different pathways, such as amylin or GIP, may result in additive or synergistic effects that enhance weight loss and improve metabolic outcomes
Patients should contact their plan provider because benefits and requirements vary
doi: 10.3390/medicina57101030 34 MaesMTwiskFNM
doi: 10.1080/07853890.2022.2076901 48 de ErausquinGASnyderHCarrilloMHosseiniAABrughaTSSeshadriS
Less common but more serious risks include pancreatitis, gallbladder disease, hypoglycemia (with insulin/sulfonylureas), kidney injury (with severe dehydration), and retinopathy worsening in patients with pre-existing diabetic retinopathy
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