Sleep hygiene measures form the cornerstone of managing insomnia: Maintain a consistent sleep-wake schedule, even on weekends Create a cool, dark, quiet sleeping environment Avoid screens (phones, tablets, computers) for at least one hour before bedtime Limit caffeine intake, particularly after midday Avoid alcohol close to bedtime Engage in regular physical activity, but not within three hours of bedtime Establish a relaxing pre-sleep routine (reading, gentle stretching, meditation) Dietary considerations may also prove helpful
naltrexone/bupropion is contraindicated in seizure disorders, uncontrolled hypertension, and those taking opioids
DHT pathway
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However, it never received FDA approval because the results, while positive, weren't dramatic enough to meet regulatory thresholds for an obesity drug