If diarrhoea is significant, oral rehydration solutions (available from pharmacies) can help replace lost fluids and electrolytes
Treat vomiting within three hours of taking your pill as a missed dose and use backup contraception for seven days
Significant weight loss contributes substantially to lipid improvements, with weight reduction varying by populationup to approximately 20% in people with obesity without diabetes (SURMOUNT-1) and generally less in those with type 2 diabetes
Medications that activate the GLP-1 receptor can help reduce blood sugar levels and promote weight loss by increasing insulin secretion and decreasing appetite

Seek urgent medical attention (call 999 or go to A&E) if you experience : Severe, persistent abdominal pain, particularly if radiating to the back (possible pancreatitis) Severe allergic reaction (difficulty breathing, swelling of face or throat, rapid heartbeat) Contact your GP or diabetes specialist nurse promptly if you experience : Persistent vomiting that prevents adequate fluid intake Signs of dehydration (dark urine, dizziness, reduced urination) Right upper abdominal pain, fever or yellowing of the skin/eyes (possible gallbladder disease) Prolonged diarrhoea or vomiting that could lead to dehydration and kidney problems In cases of intolerable gastrointestinal side effects, healthcare professionals may consider temporarily reducing the dose or, if symptoms persist, discontinuing the medication and exploring alternative therapeutic options in line with NICE guidelines for type 2 diabetes management