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Leptin binds to its receptor present on AGRP and NPY neurons and inhibits their firing resulting in reduced GABA release onto POMC neurons

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FOR LABORATORY RESEARCH USE ONLY NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE Safety Classification: For use by qualified research personnel only Keep detailed records of usage and storage as per UK research regulations Legal Notice: This product is exclusively intended for in vitro laboratory research conducted in controlled environments by qualified research staff

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extract SHR-5 in the treatment of mild to moderate depression Nordic Journal of Psychiatry (2007), DOI: 10.1080/08039480701643290 6

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IA diseases occur in patients as young as 20 or 30, while OA is usually seen in those over 50

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GSH:GSSG ratio indicates cellular redox state

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