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Ive heard of people reporting the worst upper stomach pain imaginable along with persistent nausea, thankfully not my own patients, and thats exactly the symptom cluster we worry about with pancreatitis, he said
Mechanistically, GLP1R is expressed at low levels in the heart and vasculature, raising the possibility that GLP1 might have both direct and indirect actions on the cardiovascular system
10.1161/JAHA.115.002767 54
Some people use a lower-carb approach for the first 2-4 weeks of GLP-1 treatment to manage blood sugar spikes
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