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Blood samples were immediately centrifuged, and plasma was transferred to pre-prepared tubes containing acetonitrile and an internal standard of Nle-YI-(6) aminohexanoic amide, 100 g/ml in isotonic saline

A 2021 mechanistic paper by Lu and Tonissen in Bioscience Reports detailed how the thioredoxin and glutathione systems cooperatively regulate melanogenesis pathways at the redox level, providing biochemical depth to the skin-lightening observation

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Product specifications CAS Registry Number 137525-51-0 Reported purity 99.0% Form Lyophilized laboratory research material Intended use Qualified in vitro laboratory research only