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Ethics declarations Ethics approval and consent to participate All experiments and procedures were conducted in accordance with the Regulations on the Management of Laboratory Animals issued by the National Science and Technology Commission and were approved by the Animal Ethics Association of the Hebei General Hospital (Approval Number:202332)

For researchers focused purely on pigmentation with minimal confounding variables, MT-1 is often the superior choice

A stronger barrier also allows for better retention of nutrients, which is helpful for dry or sensitive areas

These symptoms can escalate to life-threatening difficulties for individuals with comorbidities such as type II diabetes, frailty, heart disease and general aging

The Journal of Clinical Endocrinology & Metabolism , 91 (12): 5013-5018