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Kaufmans fear is that both trials will fail because too many patients will suffer side effects and withdraw, and the drug will be forever lost to vast majority of long-COVID patients
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Retatrutide is a triple agonist acting on GLP-1, GIP, and glucagon receptors, with phase 2 data published in the New England Journal of Medicine (2023) showing substantial weight reduction
[2] Heres what we know about side effects from the STEP UP clinical trial so far: Around 1 in 3 patients taking Wegovy 7.2 mg experienced nausea Around 1 in 6 patients experienced diarrhoea Around 1 in 6 patients experienced vomiting Around 1 in 7 patients experienced constipation A side effect called 'dysaesthesia' was also noted in the STEP UP trial, occurring in nearly 1 in 4 of participants taking Wegovy 7.2 mg
While semaglutide medications like Ozempic and Wegovy are some of the most sought-after treatments for weight loss right now, many people still hesitate to start them
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