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However, snails exposed to microplastics showed a 75% increase in the mean movement (0.07 cm/min), and those exposed to ibuprofen alone showed a 50% increase (0.06 cm/min) compared to the control

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Importantly, Nrf2 is a necessary transcription factor that regulates the cellular oxidative stress reaction and also controls Fe 2+ , which is manifested as an inhibition of ferroptosis (27, 66)

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[3] [9] Those with neurological symptoms may require more frequent dosing initially (alternate days until improvement) followed by two-monthly maintenance